What do we expect in the future?
As the technology of tissue engineering are developing exponentially within these 10 years, we can expect a lot from the future. Ideas such as growing a whole organ with science, further development of IPS heart cells and with the integration of AI technology implemented in this field.
The concept of building whole organ using tissue engineering is not a dream, the current advancement of technology allows scientist to grow repairing tissues and use it to repair part of the patient's damage organ. In the future, building an entire functional organs for transplantation would potentially be possible. Some strategies such as Decellularization-Recellularization would be able to remove all cellular components, leaving the ECM (extracellular matrix) behind, followed by introducing regentivie tissue into the scaffold. Others technique such as bioprinting of organs would print complex geometries, including vasculature, to mimic the native organ structure. However, the current challenges encountered are like achieving vascularization that sustains the organaving and the immune compatibility and integration with host systems.
The use of Artificial Intelligence in tissue engineering hopes to optimise and tailor make different cell size in order for consistent nutrient flow and growth to occur. Others application such as data integration and analysis, disease and drug testing, and predicting how the stem cells would behave during the growth state are also essential and possible methods to use AI in tissue engineering. Therefore, the integration of AI with robotics and bio-manufacturing could make personalized tissue engineered organs faster, cheaper, and more reproducible.